NIH basks in broad support

Opinion: NIH must support broadly focused basic research.

The NIH undertook a daring and radical research strategy after World War II. Previously, the Institute had mostly supported medical research with a disease or public health focus. Heeding the call of visionary leaders, such as Vannevar Bush, and with the support of the US Congress, the scope of NIH-funded basic research was expanded to encompass any organism that could be used to address fundam...

NIH Support for the Emergence of Quantitative and Systems Pharmacology

In recent years, the National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health (NIH) has sought to explore the integration between systems biology and pharmacology, believing that systems approaches are needed to understand the complexity of drug action and that studies of drug action will yield new insights into systems biology. To this end, NIGMS sponsored th...

Ability of New Innovator Awardees to Obtain Subsequent NIH Support

NLM NIH at TREC 2016 Clinical Decision Support Track

In this paper, we present our approach for TREC 2016 Clinical Decision Support (CDS) track. We combined methods for question analysis, query expansion, document retrieval and result fusion to find relevant documents to a given clinical question. We submitted three automatic runs using the summaries and two automatic runs using the notes, provided for the first time at the CDS track. Our experim...

The conception of the ABCD study: From substance use to a broad NIH collaboration

Adolescence is a time of dramatic changes in brain structure and function, and the adolescent brain is highly susceptible to being altered by experiences like substance use. However, there is much we have yet to learn about how these experiences influence brain development, how they promote or interfere with later health outcomes, or even what healthy brain development looks like. A large longi...